What is Axonics Therapy?

Axonics Therapy is an effective solution for treating symptoms of bowel (fecal) incontinence, overactive bladder including urinary urgency incontinence, and urinary retention.¹

What is Bowel Incontinence?

• Bowel incontinence, or accidental bowel leakage, is a condition where people get sudden urges to pass stool or experience leakage of stool before they make it to the restroom

Bowel Incontinence Symptoms

You may be suffering from bowel incontinence if:

• Fecal Urgency: You experience sudden urges to pass stool
• Urgency Fecal Incontinence: You experience an inability to stop the urge to pass stool
• Passive Bowel Incontinence: You experience leakage of stool with activity or without awareness

Did you know that patients can suffer from dual incontinence?

Dual incontinence is when a patient is experiencing both bowel and bladder control symptoms.

Bowel Incontinence Patient Care Pathway

Your doctor and his or her clinical team will follow a patient care pathway, which is a roadmap of the different treatment options available to you. The pathway starts with conservative treatments and then moves on to the advanced therapies.

Your journey to find the treatment solution that works for you

Consult With Your Doctor

• Discuss your symptoms
• Start a baseline bowel diary
• Undergo recommended diagnostic tests
• Discuss treatment options

Initial Treatment

• Diet changes
• Sphincter and pelvic floor exercises
• Over-the-counter antidiarrheal medications
• Pessary

Advanced Therapies

• Minimally Invasive
• Sacral Neuromodulation
• Invasive
• Surgical Sphincter Repair

No symptom improvements?
Don't give up!

Follow up with your doctor to discuss advanced therapy options

How does Axonics Therapy work?

Axonics Therapy provides gentle stimulation to the nerves that control the bowel and bladder, which can restore normal control and result in symptom improvement.

The Evaluation Step: To see if Axonics Therapy is right for you, you will undergo a short period of therapy using a temporary system. The evaluation period allows you to experience the level of symptom relief the therapy may provide before you commit to long-term therapy.

Long-term Therapy: If you and your doctor determine that Axonics Therapy is right for you, you will have an outpatient procedure where the miniaturized Axonics implant is placed just beneath the skin in the upper part of your buttock.

Clinically Proven. Patient Approved.

Backed by clinical studies, Axonics Therapy is clinically proven to help regain bowel and bladder control and deliver clinically meaningful improvement in quality of life.

At 2-Years,

87% of patients had ≥50% reduction in FI symptoms²

82% of patients* were satisfied with the therapy for FI symptoms¹

<2% of patients reported discomfort at the implant site¹

Want to hear from a real person about their experience with Axonics Therapy?

Doris K.

71 years old

"I adjusted my whole life by limiting myself from drinking and eating. Now I don't have to."

Doris had suffered with overactive bowel and bladder symptoms since 1987. "The thing that stands out in my mind the most is that this has gone on for so many years and I had to adjust my whole life." Finally, with Sacral Neuromodulation therapy from Axonics, Doris got her symptoms under control and was able to say "goodbye" to wearing pads!

Results and experiences may vary and are unique to each patient.

Who is a good candidate for Axonics Therapy?

It is up to you and your healthcare provider to determine if you are a good candidate for Axonics Therapy.

Axonics Therapy is an approved treatment for patients suffering with:

• Fecal (bowel) incontinence - sudden urges to pass stool and experience leakage of stool before making it to the restroom
• Overactive bladder (OAB) - the urgent need to urinate which may result in frequent urination and/or incontinence (leakage) episodes
• Urinary frequency - the need to urinate 8 or more times a day, which may or may not be associated with urgency
• Urinary urgency incontinence (UUI) - the urgent need to urinate or trouble holding urine before making it to the restroom
• Nonobstructive urinary retention (UR) - the inability to completely empty the bladder which may result in trouble urinating or frequent small voids
• Axonics Therapy is indicated for patients who have failed conservative treatments, such as lifestyle changes, physical therapy, or medications.

Axonics Therapy is not approved for:

• Stress Incontinence
• Treating urinary symptoms caused by mechanical obstructions, such as benign prostatic hypertrophy, cancer, or urethral stricture
• Patients who have not demonstrated an appropriate response to an external trial
• Patient with limited cognitive function, which may make it difficult to manage their therapy
• Pregnant women, the unborn fetus, and during delivery
• Pediatric patients (under the age of 18 years for Fl and under the age of 16 years for OAB and UR)
• Patients with neurological disease origins, such as multiple sclerosis or diabetes

Get the symptom relief you deserve!

Ready to take the first step towards symptom relief? Schedule a consultation with your doctor to discuss your symptoms and to determine if Axonics Therapy is right for you.

[LINK: Schedule Appointment]

Important Safety Information:

Implantation and use of the Axonics System incurs risk beyond those normally associated with surgery, some of which may necessitate surgical intervention.

Results and experiences may vary and are unique to each patient. No promise or guarantee is made about specific results or experiences. Talk to your doctor about whether the Axonics System is right for you and to discuss the potential risks and benefits. For more information about safety and potential risks, go to: www.axonics.com/isi.

Caution: Federal law (USA) restricts this device to sale and use by, or on the order of, a physician.

1. Pezzella A, et al. Neurourol Urodyn. 2021

2. Jottard, K., et al. Neuromodulation: Technology at the Neural Interface 2021.